Functional assays for potency evaluation and manufacturing lot release are essential tools in the development of therapeutic antibody biologics. Promega’s cell-based Fc Effector Function Reporter Bioassays platform allows simple and robust evaluation of an antibody’s ability to activate the Fc effector function mechanism which triggers ADCC and ADCP. Furthermore, we developed a range of new Immune-Checkpoint Reporter-Based Bioassays e.g. PD-1, CTLA-4, GITR, 4-IBB, OX4O and TIGIT that provide simple, consistent and reliable cell-based assays to measure antibody function throughout the drug research and development pipeline.

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