Infectious Diseases
Infectious disease research covers a broad range of topics including microbial pathogenesis, epidemiology, immunology, and antimicrobial drug and vaccine development. Promega supplies many basic molecular biology reagents that are used extensively by researchers studying these disease processes. These products include genomic DNA, plasmid DNA and RNA extraction kits, sequencing reagents, cell health assays, cloning enzymes, and PCR systems.
In addition to these routine molecular tools, luminescence technologies such as firefly and NanoLuc® luciferase reporters and HiBiT protein tagging and detection system have found extensive application in the study of viral diseases. The small size of the Nanoluc® luciferase reporter and HiBiT tag make them particularly useful in small viral genomes, and the bright luminescence signal generated makes it possible to gain sensitivity in detecting viral activity in cells and organisms.
Viral Research, Testing and Assay Development
Infectious Disease Product Categories
Cell Health Assays
Produkte für die Analyse komplexer zellulärer und biochemischer Prozesse
Cloning and DNA Markers
Restriktionsenzyme, DNA modifizierende Enzyme, Vektoren, Molekulargewicht-Marker
Energy Metabolism
Biolumineszente Assays um die Glucoseaufnahme oder NAD(P)H-Aktivitität zu messen.
Immunoassays
Lumit® assays for fast, bioluminescent immunodetection, as well as primary and secondary antibodies and blotting reagents.
Luciferase Assays
Reporterassays, Vektoren + Zelllinien, Transfektionsreagenzien
Nucleic Acid Extraction
Hier finden Sie eine Reihe von Nukleinsäure-Extraktionskits. Von manuellen Lösungen für Einzelproben bis zu plattenbasierten Verfahren
PCR
Alles rund um die PCR, qPCR und RT-qPCR
Protein Interactions
Komplementierungs-Reporter; BRET, HaloTag und GST-basierte Protein-Interaktionsassays; Protein:DNA-Interaktionsassays
Sequencing
Produkte und Lösungen für die NGS Auf- und Nachbereitung
Example Infectious Disease Applications
Virology
Luciferases are increasingly being used to study viral infectious diseases. These bioluminescence-based methods provide highly sensitive detection of specific cellular events such as viral entry, proliferation, and viral:host protein interactions.
Cellular Immune Response
Promega cell health and energy metabolism products are applied to study many aspects of the host response to pathogens, including inflammasome activation, host cell metabolic changes and host cell viability.
Manuelle Aufreinigung
ReliaPrep™ Viral TNA Miniprep Kit, Custom
Virale RNA aus einem Transportmedium
Maxwell® HT Viral TNA Kit
Virale RNA aus Sputum (96-well)Virale RNA aus Sputum (Röhrchen)
Maxwell® Geräte
Maxwell® RSC Geräte
Virale RNA aus Transportmedien
Virale RNA aus Körperflüssigkeitens
Maxwell® 16 Geräte