PPase-2B Product Information
Literature # 9PIV636
Protein Phosphatase-2B (PPase-2B) is a heterodimeric enzyme composed of a 19kDa calcium-binding subunit and a catalytic subunit (61kDa) that binds calmodulin. PPase-2B is identical to the brain protein calcineurin, which constitutes up to 1% of total brain protein.
PPase-2B is less sensitive to okadaic acid than PPase-2A and PPase-1, requiring micromolar concentrations of okadaic acid for inhibition. It is not inhibited by inhibitor-1 or inhibitor-2. Promega PPase-2B is isolated from bovine brain.
Printed in USA. Revised 10/06.