Protein Kinases as Drug Targets in High-Throughput Systems
- Comments & Ratings
There are an estimated 2,000 kinases and 500 phophatases in the human genome, and almost one-third of all proteins in a cell can be phosphorylated. The completion of sequencing of the human genome and other genomes may lead to the discovery of additional kinases and phosphatases, many of which could be implicated in the regulation of cell growth. With these discoveries comes the need for novel reagents and specific assays to identify potential gene products and to characterize these enzymes and their functions in the cell.
Promega Notes 75, 24–28.
Publication Date: 2000