Promega Corporation

Power of Discrimination

The PowerPlex® and GenePrint® Systems provide powerful discrimination. Population statistics for the loci and their various multiplex combinations are listed here. These data were developed as part of a collaboration with The Bode Technology Group (Springfield, VA), North Carolina Bureau of Investigation (Raleigh, NC), Palm Beach County Sheriff’s Office (West Palm Beach, FL), Virginia Division of Forensic Science (Richmond, VA) and Charlotte/Mecklenburg Police Department Laboratory (NC). Generation of these data includes analysis of over two hundred individuals from African-American, Caucasian-American and Hispanic-American populations. Data for Asian-Americans includes analysis of over 150 individuals.

A measure of discrimination often used in paternity analyses is the paternity index (PI), a means for presenting the genetic odds in favor of paternity given the genotypes for the mother, child and alleged father. An alternative calculation used in paternity analyses is the power of exclusion.

Matching Probabilities of Various Populations
Paternity Indices in Various Populations
Power of Exclusion in Various Populations

Matching Probabilities of Various Populations
STR Multiplex System African-American Caucasian-American Hispanic-American Asian-American
GenePrint® Silver STR Systems
CTT System
(CSF1PO, TPOX, TH01)
1 in 1,590 1 in 435 1 in 549
FFv System
(F13A01, FESFPS, vWA)
1 in 2,828 1 in 927 1 in 1,343
SilverSTR™ III System
(D16S539, D7S820, D13S317)
1 in 1,152 1 in 2,552 1 in 2,493
All 3 Silver Triplexes#(9 loci) 1 in 5.18 × 109 1 in 1.03 × 109 1 in 1.84 × 109
GenePrint® Fluorescent STR Systems
CTTv System
(CSF1PO, TPOX, TH01, vWA)
1 in 6,769 1 in 25,236 1 in 7,219
FFFL Triplex System
(F13A01, FESFPS, F13B, LPL)
1 in 2,658 1 in 16,802 1 in 3,276
GammaSTR® III Triplex
(D16S539, D7S820, D13S317, D5S818)
1 in 16,790 1 in 10,872 1 in 20,106
All 3 Fluorescent Quadriplexes
(12 loci)
1 in 3.0 × 1011 1 in 4.61 × 1012 1 in 4.75 × 1011
PowerPlex® Systems
PowerPlex® 1.1 (or 1.2) System
(8 STR loci)
1 in 2.74 × 108 1 in 1.14 × 108 1 in 1.45 × 108 1 in 1.32 × 108
PowerPlex® 2.1 System
(9 STR loci)
1 in 3.0 × 1011 1 in 8.46 × 1010 1 in 1.02 × 1011 1 in 1.52 × 1011
PowerPlex® 1.1 Plus 2.1 System
(14 STR loci)
1 in 4.19 × 1016 1 in 1.07 × 1016 1 in 1.59 × 1016 1 in 2.17 × 1016
PowerPlex® 1.1 Plus 2.1 System
Plus FFFL (18 STR loci)
1 in 7.03 × 1020 1 in 2.84 × 1019 1 in 5.21 × 1019 1 in 1.14 × 1019
PowerPlex® 16 System
(15 STR loci)
1 in 1.42 × 1018 1 in 1.83 × 1017 1 in 2.94 × 1017 1 in 3.74 × 1017
Paternity Indices in Various Populations
STR Multiplex System African-American Caucasian-American Hispanic-American Asian-American
GenePrint® Silver STR Systems
CTT System
(CSF1PO, TPOX, TH01)
10.2 6.8 5.2
FFv System
(F13A01, FESFPS, vWA)
16.0 9.8 7.8
SilverSTR™ III System
(D16S539, D7S820, D13S317)
7.6 7.7 14.1
All 3 Silver Triplexes
(9 loci)
1,233 521 563 -
GenePrint® Fluorescent STR Systems
CTTv System
(CSF1PO, TPOX, TH01, vWA)
29.4 19.26 10.51
FFFL Triplex System
(F13A01, FESFPS, F13B, LPL)
16.83 15.28 8.23
GammaSTR® III Triplex
(D16S539, D7S820, D13S317, D5S818)
16.93 13.51 30.40
All 3 Fluorescent Quadriplexes
(12 loci)
8,373 3,976 2,627
PowerPlex® Systems
PowerPlex® 1.1 (or 1.2) System
(8 STR loci)
498 260 319 471
PowerPlex® 2.1 System
(9 STR loci)
13,130 13,199 3,250 41,800
PowerPlex® 1.1 Plus 2.1 System
(14 STR loci)
6.11 × 105 4.08 × 105 1.63 × 105 2.02 × 106
PowerPlex® 1.1 Plus 2.1 System
Plus FFFL (18 STR loci)
1.03 × 107 6.24 × 106 1.34 × 106 4.55 × 106
PowerPlex® 16 System
(15 STR loci)
2,510,000 1,520,000 5,220,000 4,110,000
Power of Exclusion in Various Populations
STR Multiplex System African-American Caucasian-American Hispanic-American Asian-American
GenePrint® Silver STR Systems
CTT System
(CSF1PO, TPOX, TH01)
0.906 0.869 0.830
FFv System
(F13A01, FESFPS, vWA)
0.938 0.904 0.881
SilverSTR™ III System
(D16S539, D7S820, D13S317)
0.877 0.880 0.929
All 3 Silver Triplexes
(9 loci)
0.9993 0.9985 0.9986
GenePrint® Fluorescent STR Systems
CTTv System
(CSF1PO, TPOX, TH01, vWA)
0.967 0.953 0.918
FFFL Triplex System
(F13A01, FESFPS, F13B, LPL)
0.946 0.941 0.902
GammaSTR® III Triplex
(D16S539, D7S820, D13S317, D5S818)
0.946 0.934 0.967
All 3 Fluorescent Quadriplexes
(12 loci)
0.99990 0.99981 0.99974
PowerPlex Systems
PowerPlex® 1.1 (or 1.2) System
(8 STR loci)
0.9982125 0.9968853 0.9973337 0.9981793
PowerPlex® 2.1 System
(9 STR loci)
0.9999219 0.9999242 0.9997134 0.9999759
PowerPlex® 1.1 Plus 2.1 System
(14 STR loci)
0.9999988 0.9999982 0.9999951 0.9999995
PowerPlex® 1.1 Plus 2.1 System
Plus FFFL (18 STR loci)
0.9999999 0.9999999 0.9999995 0.9999999
PowerPlex® 16 System
(15 STR loci)
0.9999996 0.9999994 0.9999983 0.9999998

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